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Benalapril (Enalapril)
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Benalapril

Benalapril is a prescription medicine used to treat symptoms of high blood pressure (hypertension), left ventricular dysfunction and congestive heart failure. Benalapril may be used alone or with other medications. Benalapril belongs to a class of drugs called ACE Inhibitors.

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Also known as: Enalapril

Description

Benalapril (enalapril) is an ACE inhibitor. ACE stands for angiotensin converting enzyme.

Benalapril is used to treat high blood pressure (hypertension) in adults and children who are at least 1 month old.

Benalapril is also used to treat congestive heart failure in adults.

Benalapril is also used to treat a disorder of the ventricles (the lower chambers of the heart that allow blood to flow out of the heart). This disorder can decrease the heart's ability to pump blood to the body.

Dosage

Usual Adult Dose for Hypertension:

Initial dose: 5 mg orally once a day Maintenance dose: 10 to 40 mg orally per day as a single dose or in 2 divided doses Maximum dose: 40 mg orally daily as a single dose or in 2 divided doses In combination with diuretics: Initial dose: 2.5 mg orally once a day If feasible, the diuretic should be discontinued 2 to 3 days prior to initiation of therapy with enalapril. If required, diuretic therapy may be gradually resumed.

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 2.5 mg orally once a day Maintenance dose: 2.5 to 20 mg daily in 2 divided doses Maximum dose: 40 mg orally per day in 2 divided doses Comments: -Treatment is usually combined with diuretics and digitalis. -Doses should be titrated upward, as tolerated, over a period of a few days or weeks.

Usual Adult Dose for Left Ventricular Dysfunction:

Initial dose: 2.5 mg orally twice a day Maintenance dose: 20 mg orally per day in 2 divided doses Comments: -After the initial dose, the patient should be observed for at least 2 hours and until blood pressure has stabilized for at least an additional hour. -If possible, the dose of any concomitant diuretic should be reduced which may diminish the likelihood of hypotension.

Usual Pediatric Dose for Hypertension:

Children 1 month to 17 years: Initial dose: 0.08 mg/kg/day (up to 5 mg) in 1 to 2 divided doses. Adjust dosage based on patient response. Maximum dose: Doses greater than 0.58 mg/kg (40 mg) have not been evaluated in pediatric patients. Comment: -Not recommended in neonates and in pediatric patients with glomerular filtration rate less than 30 mL/min, as no data are available.

Detailed Benalapril dosage information

Overdose

If you overdose Benalapril and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Benalapril overdosage: fainting, dizziness.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Benalapril are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

No information is available on the relationship of age to the effects of enalaprilat in geriatric patients. However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment of dose in patients receiving enalaprilat .

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Technetium-99m-d, 1-HM-PAO: a new radiopharmaceutical for imaging regional brain perfusion using SPECT--a comparison with iodine-123 HIPDM. Analgesic properties of a systemically-administered synthetic dipeptide of 5-hydroxytryptophan. Renal and hepatic uptake of biologically active intact parathyroid hormone. Control of massive hemorrhage from rectal varices with sclerotherapy. A trans activity of the VP4 protease of IBDV, and also IPNV VP4 protease, was demonstrated by co-expression of VP4 and a polypeptide substrate in Escherichia coli. In all treatments, g(m) and A(n) increased and CO(2) drawdown because of g(m) , C(i) -C(c) , decreased with increasing leaf age. Our data show that the syndecan-1 and glypican-1 mRNA expression is increased by the phorbol myristate acetate (PMA) suggesting a regulation of their expression by the phosphatidyl inositol pathway, as previously hypothesized (Fagen et al., Biochim. Surgical Mentorship: A Great Tradition, But Can We Do Better for the Next Generation?. In this setting, we could readily visualize IN both in producer cells and in viral particles. Reliability and validity estimates did not differ with type of neighborhood.

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