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Alprozam (Alprazolam)

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Alprozam is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprozam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprozam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alpanol, Alpaz, Alpradol, Alpramax, Alpranex, Alprasan, Alprogard, Alprotame, Alprowon, Altalin, Alzoact, Alzoset, Ambulax, Ambusyn, Anxitab, Avizolem, Azolam, Depsolam, Diprex, Elflu, Esteem, Fluxin, Fluxozam, Jolistar, Mebaspa, Nexlpra, Nitril, Prolam, Proprazolam, Prozam, Restam, Romipraz, Rozin, Selamb, Sinozol, Tenlax, Tensyn, Texidep, Tranax, Trazopin, Viprax, Visram, Xycalm, Xylonite, Zenax, Zocam, Zoloid, Zopain, Zopic, Zotam

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Coreg, Eriacta, Zovirax, Glucotrol, Pyridium, Mircette, Cefpodoxim, Prestole, Marax, Clasine, Tininum, Zolase, Metrozole, Ranspas,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprozam. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


If you have been prescribed Alprozam for medical reasons, the best way to avoid a Alprozam overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alprozam consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alprozam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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The induction of VEGF by progestins is also cell type specific and does not occur in human breast cancer cell lines MCF-7, ZR-75, or MDA-MB-231, nor in Ishikawa cells derived from a human endometrial carcinoma. After removing the muscles from the scapula, the superficial muscle fibers of each muscle were removed layer by layer until the entire intramuscular tendon was exposed. This algorithm was confirmed by means of computer simulation studies. Leiomyomas of the deep soft tissue in the extremities of children are very rare. Isolation of Trypanosoma cruzi DNA in 4,000-year-old mummified human tissue from northern Chile.

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The conceptualization is relevant to diverse racial/ethnic groups, considers the larger social and historical context, and incorporates attention to culture-based variables that may mediate the relationship between racism and well-being. Molecular analysis for 35 Y chromosomal loci was performed for DNA samples taken from peripheral leukocytes and lymphoblastoid cell lines, showing that the four patients shared the region between DYS267 at interval 4A and DYF50S1 at interval 6D, with the exception of the region around DYS202 at interval 5K. Also, there is a need for research investigating online use among adults aged 65 and over - a rapidly growing demographic of Internet users. Informal assistance to urban families and the risk of household food insecurity. The cellular infiltrate found during the acute phase of multiple sclerosis (MS) consists of monocytes and activated T cells, suggesting the presence of cell-specific chemotactic signals during the inflammatory response.

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Seventy adult subjects were investigated for possible SIBO and hepatic damage with bacteriological analysis of small intestinal aspirates and measurement of serum concentrations of alkaline phosphatase, gamma-glutamyl transpeptidase, aspartate aminotransferase, and alanine aminotransferase. The MRI examinations were performed on a 1.0-T system (Magnetom, Siemens, Erlangen, Germany), and sagittal T1-weighted (550/17 TR/TE) and T2-weighted (2000/80 TR/TE) spin-echo (SE) images of the pelvis were obtained. Because aging involves a detrimental immune response, this work aimed to assess the possible role of chronic low-grade immune stimulation on frailty status in the elderly. A diet containing either 3H4MCA or 3,4DMCA should not be taken by patients bearing cancers in the seminal vesicles, spleen or liver, and a diet containing 3,4DMCA should not be taken by patients bearing cancers in the testis, kidney, muscle, small intestine or brain (cortex) because of the significant increases in polyamines, which are associated with a risk of cancer growth, in these tissues. Data extraction and content analysis via data mining techniques were performed on these articles. To describe the anatomic and technical difficulties encountered with transvaginal ultrasound imaging of the cervix in a consecutive series of women at risk for preterm delivery. Randomized controlled comparison of nitroimidazoles for the eradication of Helicobacter pylori and relief of ulcer-associated and non-ulcer dyspepsia.

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Parafibromin Staining Characteristics in Urothelial Carcinomas and Relationship with Prognostic Parameters. The total insulin (TI) level was also measured by the nonspecific assay. An electrochemically active compound was detected in the larvae of Aedes aegypti mosquitoes and progressive accumulation of this compound was observed during larval development. Thirty premature infants with significant lung disease, requiring furosemide after a red cell infusion. However, there were no significant associations between the CCS and any independent variables. RT-PCR results showed that naringin could upregulate the expression of miR-19b mRNA.

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Suppression of terminal axonal sprouting at the neuromuscular junction by monoclonal antibodies against a muscle-derived antigen of 56,000 daltons. Accurate knowledge of the surgical anatomy of the hepatic veins and inferior vena cava is indispensable for surgeons, since catastrophes usually occur in this area. The CGRP staining was similar in rat, except for CGRP positive neurons that were found close to the central canal. Their paralogous genes on chromosomal band 9q33-34 are genes for type 5 collagen alpha1 subunit (COL5A1), NOTCH1, 78 kDa glucose-regulated protein (HSPA5), valyl-tRNA synthetase 1 (VARS1), complement component V (C5), PBX3, retinoid X receptor alpha (RXRA), ORFX/RING3L, and others. Driver characteristics, such as glance location and distraction were reduced from the driver and over the shoulder videos. The chi(2) for R(2), summed over the selected sites, shows a clear minimum, as a function of tau(R). Growth retardation and fetal hydrocephalus developing after discontinuation of a mid-trimester termination procedure. All patients who underwent a partial glossectomy had difficulties with formation and anteroposterior propulsion of the bolus in the oral cavity and an increase in oral transit time, which was more evident with materials of thicker consistencies. Familial isolated hypoparathyroidism: case report with serum PTHrP examination. Magnetic resonance cholangiopancreatography in the evaluation of pancreatic duct pathology.

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Two adults (aged 71 and 74 years) developed cerebellar mutism after posterior fossa surgery for a mass lesion in the superior cerebellar hemisphere or upper vermis. Characterization of effector cells in lymphocytotoxicity to autologous hepatocytes in HBsAg-positive and autoimmune chronic active hepatitis (CAH). Production and characterization of polyclonal and monoclonal anti-anti-idiotypic antibodies. Tuberculosis among Filipino patients with systemic lupus erythematosus. Non-antioxidative mechanism of cytochrome P-450 stabilization by alpha-tocopherol: the effectiveness in avitaminosis E.

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This SFEB protocol provides a robust and scalable system for the study of developing network formation in a 3-D model that captures aspects of early cortical development. Little is known about the long-term psychosocial functioning of children with esophageal atresia (EA). Analytical approaches for determining human exposure to pesticides. Hymenolepis diminuta: metacestode-induced reduction in the synthesis of the yolk protein, vitellogenin, in the fat body of Tenebrio molitor. The goal of this research was to verify if these groups comprise workers at different levels of risk of occurrence of complete work disability related to back injury. Detection of methylation on dsDNA using nanopores in a MoS2 membrane. This study concerns 65 neuro surgical patients operated on under Electrical Analgesia method. These results suggest that astrocytes in an inflammatory environment have the capacity to express the required MHC class II and B7 costimulatory molecules necessary for efficient activation of naive T cells.

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This enzyme is encoded by a 5.1-kilobase mRNA expressed exclusively in the brain. By contrast, liposomes containing RNP and the variant G protein induced a good protective response, comparable to that achieved with inactivated virus vaccine against intracerebral challenge. The following experimental evidence is provided in support of this mechanism. For electropermeabilization in vitro, we used YTS-1 cells, a human transitional cell carcinoma line. This article presents projected future drought occurrences in five river basins in Virginia. Temperature during cardiopulmonary bypass for coronary artery operations does not levaquin iv dose influence postoperative cognitive function: a prospective, randomized trial. MYB transcription factors (TFs) are important regulators of flavonoid biosynthesis in plants.

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Results of postoperative clinical examination of inguinal hernia after three years. A significant minority said that the presence of a student improves the consultation. In conclusion, dithioerythritol improves cell and mediator recovery without causing cell activation when sputum processing is conducted at room temperature. In SM, IFN gamma was detectable in all patients, while the other cytokines were less frequently found. Ranitidine (10(-2) M) increased 4 times the number of sites of glucocorticoid receptor binding for acetonide triamcinolone and aroused the association constant of hormone-receptor complex. Chlorophyll a fluorescence and P700 absorbance measurements revealed that the activities of the two photosystems declined in parallel. Interestingly, studies with cultured Aplysia neurons indicated that removing a CREB repressor promoted the formation of long-term facilitation, a cellular model of non-associative memory.

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Better understanding of the genetic mechanisms underlying bladder tumor development and progression will allow better prevention, diagnosis, and treatment strategies. Our data show that long-term tamoxifen treatment blocks the response of GH to exogenous GHRH and reduces IGF-1 levels, possibly by a central mechanism other than the demonstrated peripheral action. An infrared spectroscopy method to detect ammonia in gastric juice. Mo2C nanoparticles with sizes ranging from 5 to 50 nm are uniformly supported by surrounding graphite layers. Therefore, it is suggested that clonidine activated alpha 1- acticin like adrenoceptors. Evaluation of the results of high-speed handpiece and minimally invasive extraction in impacted mandibular third molar extraction. Furthermore, initiation of therapy (steroids and/or cytotoxic agents) early in the course of disease is predictive of a better response. To compare the magnitude of multivariable coefficients and hazard ratios of four cardiovascular risk factors across five worldwide regions of the Seven Countries Study in predicting 50-year coronary deaths. Clinical use of this technique would reduce the ensemble needed for averaging while obtaining the same diagnostic result. Among them one can see subjects with normal glucose tolerance that is accompanied with high serum C-peptide and insulin concentration.

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We hope that these data will encourage greater awareness of the role that improved sleep hygiene may play in the management of these rheumatic diseases. Responses to pituitary adenylate cyclase polypeptide (PACAP)-27, PACAP-38, and vasoactive intestinal peptide (VIP) were compared in the peripheral and pulmonary vascular beds of the cat and in the isolated perfused neonatal pig heart. What is the prior probability of a proposed new treatment being superior to established treatments?. Patients with symptoms and microscopic evidence of vaginitis at the initial visit were followed through pregnancy but were not analyzed with asymptomatic individuals who had vaginal cultures for Candida at the first visit and at subsequent visits if they developed vulvovaginal symptoms. Mosquito seasonality and vasotec mg arboviral disease incidence in Murray Valley, southeast Australia. The electric field confinement leads to major advantages such as low power requirements, higher qubit densities and faster gate times.

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Two cattle died acutely after being sprayed for lice control with a cyclodiene organochlorine insecticide, endosulfan, not labelled for use in cattle. Furthermore, continuous intrathecal analgesia was also continued in the post-operative period and provided effective pain relief that was reflected by the favourable surgical outcome. Wires in the as-received state and wires subjected to a 1-min heat treatment at different temperatures were tested. Accurate imaging of the renal vasculature, however, is essential for the proper selection of those individuals who might best benefit from such intervention. Primary linitis plastica of the rectosigmoid in a thirteen year old boy. Precision medicine approaches to lung adenocarcinoma with concomitant MET and HER2 amplification. A comprehensive study was made of the parameters of antioxidative defense in patients with chronic nonspecific pulmonary diseases (CNSPD), malignant and benign respiratory tumors. Human embryonic development after blastomere removal: a time-lapse analysis. Those who reported exercising at least 6 times per month with an intensity corresponding to at least vigorous walking for a mean duration of 30 minutes were classified as conditioning exercisers, those who reported no leisure physical activity were classified as sedentary, and other subjects were classified as occasional exercisers.

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Chondromyxoid fibroma is a rare benign tumor that usually occurs in the long bones. Ecchymotic cellulitis in infants should, in the first place, evoke an Haemophilus influenzae infection. Evaluation of microleakage of composite restorations with glass insert megafillers. A combination of epitope design, pH optimization, and the additive l-arginine permitted the recovery of soluble VP1 pentamers presenting hydrophobic epitopes and their subsequent assembly into virus-like particles. The results of these 4 years show that pregnancy in women aged 35 and over is burdened with a greater incidence of maternal complications and cesarean sections, but age is not a risperdal dispersible tablet risk for neonatal outcomes. Data were analysed using simple descriptive, multiple regression and complex multi-level modelling techniques, accounting for practice clustering of patients.

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Female clients in LDI and LC visits were equally likely to be tested for Chlamydia. By measuring left ventricular diastolic function and arterial stiffness, this study aims to probe into the effect of diabetes mellitus (DM) on left ventricular diastolic function and arterial stiffness, and evaluate the correlation between left ventricular diastolic function and arterial stiffness. Escape from cellular aging is the rate-limiting step of multistep carcinogenesis. Further investigations are needed to establish OC as a trait or a state. Patients with evidence of calcium in a commissure have a lower survival rate and a higher incidence of mitral valve replacement and all end points combined. A patient is presented with cranial nerve dysfunction which was attributed to a meningeal involvement of chronic lymphocytic leukemia of the B cell type. The case is presented of an elderly woman with normal left ventricular (LV) systolic function and VVI pacing complicated by severe congestive heart failure. Bet v 1, the major birch pollen allergen, conjugated to crystalline bacterial cell surface proteins, expands allergen-specific T cells of the Th1/Th0 phenotype in vitro by induction of IL-12.

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Toxicities including fever, flu-like symptoms and dose-limiting hypotension can be severe yet manageable, and IL-1 can be given safely to human cancer patients. It was first clearly identified the dysregulated expression of BUB1B and SLPI in NPC tissues. This study was conducted in order to evaluate the attention capacity during the school day and week, taking school life and others factors into account in 10,000 children (8 to 11 years old) in public Parisian schools. The results did not confirm the initial hypothesis, but imply that PCOS is associated with increased GR protein concentration and HPA axis sensitivity to dexamethasone. We studied 57 patients with early prostate cancer who were treated with free (125)I transperineal brachytherapy. gallinaceum block sporozoite invasion of mosquito salivary glands, as well as abrogate the infectivity of sporozoites to a vertebrate host, the chicken, Gallus gallus, and block sporozoite invasion and development in susceptible cell lines in vitro. A cytosolic, galphaq- and betagamma-insensitive splice variant of phospholipase C-beta4.

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In reverse anatomy TSA designs used for unstable joints, fixation is particularly demanding. Hepatobiliopancreatic surgery in patients over 70 years old: which anesthesia?. Knockdown of smed-pabpc2 leads to defects in epidermal lineage specification, disorganization of epidermis and ECM, and deregulated wound healing, resulting in the selective failure of neoblast proliferation near the wound region. Prostate cancer is the most common tumour in men, and is most frequently established late in life. We investigated whether drugs approved by the Food and Drug Administration (FDA) through expedited review have offered larger health gains, compared to drugs approved through conventional review processes. Genetic differences between the endangered San Clemente Island clomid fertility dosage loggerhead shrike Lanius ludovicianus mearnsi and two neighbouring subspecies demonstrated by mtDNA control region and cytochrome b sequence variation. Three cases of coronary to pulmonary arterial fistulae combined with valvular disease. Clinically important adrenal insufficiency was defined as the need for exogenous corticosteroid replacement for suspected adrenal insufficiency at any time during hospitalization. We also evaluate the more specific hypothesis that the difference in work-related anger between front-line supervisors and nonsupervisory workers will be relatively larger among workers in the commodified services sector than other sectors. By exploring the spatial organization of the Kcnq1 locus, our results reveal a novel mechanism by which local activation of genes can override the regional silencing effects of non-coding RNAs.

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