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Alpradol (Alprazolam)
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Alpradol

Alpradol is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alpradol is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alpradol may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Alprop, Alprose, Alprosym, Alzopam, Andep, Anxorel, Cqlam, Depwell, Exiten, Fledore, Golprax, Manzolam, Mebrin, Proprazolam, Resta, Restyl, Somnarest, Synozolam, Tenlax, Trustin, Visram, Zepro, Zocam, Zolam, Zoltweet, Zotam

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Also known as: Alprazolam

Description

Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.

Dosage

Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alpradol dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alpradol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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Catecholamine storage vesicles as a reservoir for the rapid release of t-PA. Synthesis and structure studies of complexes of some second row transition metals with 1-(phenylacetyl and phenoxyacetyl)-4-phenyl-3-thiosemicarbazide. Sulfonylurea (chlorpropamide or glyburide), insulin, or metformin (if patients were obese). Vulnerable Youth as Prosumers in HIV Prevention: Studies Using Participatory Action Research. All patients underwent laparoscopy for the treatment of DIE and had their RLUs removed when there was shortening, deviation, or thickening. The incidence of early gastric cancer has not increased despite better access to endoscopic facilities for general practitioners. These issues are discussed and points of interaction among them are examined. The Use of Deconstructed Tires as Elastic Elements in Railway Tracks. Evaluation of Candida acidothermophilum in ethanol production from lignocellulosic biomass. Evidence that the receptor for C4a is distinct from the C3a receptor.

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The steroid monooxygenase is concluded to have the activities of both oxygenative esterification of 20-ketosteroids and oxygenative lactonization of 17-ketosteroids. The model of pentylenetetrazol-induced status epilepticus in the immature rat: short- and long-term effects. Angiographically defined primary angiitis of the CNS: is it really benign?. None of the 11 anti-alpha derived from denatured AChR bound to the main immunogenic region (MIR) as judged by antibody competition assays. VP1 was labelled with glucosamine and is probably a glycoprotein. Modeling emotional reactivity and sensation/novelty seeking with the Roman/Verh rat lines/strains: an introduction. All the cases occurred in the part of the factory where air concentrations of cobalt were the lowest. qRT-PCR analysis of 8 selected CsSOD genes showed that these genes could respond to heat, cold, osmotic, and salt stresses. In recent years it has been demonstrated that both GH deficiency and excess include in their advanced clinical manifestations an impaired cardiovascular function, which may reduce life expectancy.

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Monolayer graphene has poor absorption in the near-infrared region. A limited antibody panel can distinguish B-precursor acute lymphoblastic leukemia from normal B precursors with four color flow cytometry: implications for residual disease detection. Compounds 1-8 were isolated from Bufonis periostracum for the first time and compounds 3, 5, 6, 7 were obtained from Bufo bufo gargarizans and Bufo genus for the first time. Results from the Study 2 indicated that the persistent efficacy of doramectin was 18 days on the basis of mite recovery. Subcellular targeting and biosynthesis of cyclotides in plant cells. However, there is limited evidence for its utility in the environment of active or senescent infection. One way to advance understanding is by identifying characteristics of individuals that reliably covary with memory performance.

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A comparison of two-fingers technique and two-thumbs encircling hands technique of chest compression in neonates. A 33-year-old patient with history of dyspepsia underwent imaging studies suggestive of a neuroendocrine tumor. The effect of neutron absorption and scattering was evaluated, as well as the absorption and production of gamma rays in the phantom. The animals were kept under control until the end of the experiments. Urgent computed tomography scans of the orbit and chest were performed, and emergency systemic treatment with nasogastric decompression and antibiotics was initiated. In endometriotic stromal cells, overactivation of the phosphatidylinositol 3-kinase/AKT signaling pathway contributes to the reduced expression of the decidua-specific gene, IGFBP1, potentially through reduced levels of nuclear FOXO1.

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The use of echography in prenatal diagnosis in problems of familial cyclopia. Herein, we demonstrate the utility of the precision-cut placental slice culture model for studying trophoblastic diseases. CT coronary angiography findings in non-atherosclerotic coronary artery diseases. Where the results of frozen section were acted upon, in 5 of 9 patients with an inadequate excision, only 1 fatal dehiscence occurred compared with fatal dehiscence in all 4 patients where a second excision was not performed. Origins of coevolution between residues distant in protein 3D structures.

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HIV-tuberculosis-associated immune reconstitution inflammatory syndrome is characterized by Toll-like receptor and inflammasome signalling. This study investigates topographic changes after strabismus surgery in human beings. This is the first report of gelsolin-related familial amyloidosis in a Brazilian family, and the result is particularly significant as this pedigree presents an unusual mutation, described previously in three families, with no known Finnish ancestors (Danish type). Serum VEGF-B is significantly higher in women with polycystic ovary syndrome and is closely and positively related to insulin resistance. Antiplatelet antibodies in patients with acute myocardial infarct.

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Combination of sofosbuvir and daclatasvir in the treatment of genotype 3 chronic hepatitis C virus infection in patients on maintenance hemodialysis. Cigarette smoking causes biochemical changes in blood that are suggestive of oxidative stress: a case-control study. Artificial sweetener use among children: epidemiology, recommendations, metabolic outcomes, and future directions. Hence, some guidelines are given, in particular with regard to the use of mefloquine as a prophylactic drug. V/M was computed in 238 patients from the NXT trial who underwent coronary computed tomography angiography (CTA), quantitative coronary angiography (QCA) and FFR measurement in 438 vessels. A group of 1-thio-beta-L-fucopyranosides containing hexadecane, 9-octadecene, adamantane, 1,2-diphenyltetrafluoroethane, and 3-hexynyl- and 3,6-dioxaoctylcholesterols were synthesized as potential immunologic adjuvants. The results indicate a high level of heterogeneity between the studies for all the assessed areas.

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