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Alpracon (Alprazolam)

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Alpracon is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpracon, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpracon is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aaram, Alamflu, Alparazole, Alpkair, Alprac, Alprawin, Alzocum, Alzokam, Alzolite, Alzorix, Alzotime, Anxicalm, Anxigo, Anxit, Anxyl, Betapax, Elflu, Emcalm, Flumusa, Flunix, Niravam, Norex, Notens, Pifzot, Prolam, Proprazolam, Richpram, Sanprazole, Suzilam, Texidep, Tryzo, Xycalm, Zolent, Zolin, Zopam

Similar Products:
Tofranil, Zantac, Indocin, Aristocort, Nolvadex, Ovral, Ilosone, Azitrobac, Zytol, Nitrofurantoin, Amone, Gabpam, Helmanil, Vectoryl,

Also known as: Alprazolam


Alpracon is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Alpracon is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Alpracon if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Alpracon or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Alpracon. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


Take Alpracon XR exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Alpracon XR may be habit-forming and should be used only by the person it was prescribed for. Alpracon XR should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not crush, chew, or break a Alpracon extended-release tablet. Swallow the tablet whole. It is specially made to release alprazolam slowly in the body. Breaking the tablet would cause too much alprazolam to be released at one time.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

Your symptoms may return when you stop using Alpracon XR after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Alpracon XR.

Withdrawal symptoms may include blurred vision, trouble concentrating, loss of appetite, diarrhea, muscle twitching, numbness or tingling, or increased sensations.

Do not stop using Alpracon XR suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Alpracon XR at room temperature away from moisture, heat, and light. Remove any cotton from the bottle of disintegrating tablets, and keep the bottle tightly closed.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Detailed Alpracon XR dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpracon dosage information

Side effects

The most common side effects associated with Alpracon are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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The availability of iodized salt is well under the WHO recommendation in Dabat District in spite of the fact that Ethiopia has been implementing universal salt iodization since the last five years. We examined 348 knees in 174 newborns using ultrasonography, concentrating especially on the trochlea femoris. A survey on the advances of the fight against malaria is given, and the present world-wide situation of this disease is described including the important role World Health Organization (WHO) is playing in this fight. The use of the DPS map was analyzed retrospectively in 53 patients (32-84 years old) who underwent dynamic contrast-enhanced MRI of the breast. Simultaneous modulation of GSK3b and ERK1/2 pathways might be an interesting strategy to reduce IRI in steatotic livers with an impairment of autophagy.

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In the present paper, malignant and nonmalignant human cells were compared in their response to a fraction (fraction D, FD) of a human placental extract. New features are discussed, as well as developments in the community of contributors. This multiple combined indirect procedure can cover a wider area of the ischemic brain through the EMAS in the frontal and the EDAS and EMS in the temporo-parietal regions. To examine the effect of oxygen on apneas and sleep quality in patients with frequent central apneas during sleep. p53 expression was observed significantly more frequently in bronchiolar dysplasias with pneumoconiosis than in those from non-pneumoconiotic patients (13 of 23 vs. Heart failure (HF) is a serious debilitating condition with poor survival rates and an increasing level of prevalence. The implication of this extensive heterogeneity is that each of the disorders leading to peptic ulcer may have a distinct etiology, pathophysiology, genetics, and natural history, and thus may be amenable to different modes of therapy and prevention.

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Visceral leishmaniasis is an important parasitic disease of the developing world with a limited arsenal of drugs available for treatment. Variation in epidermal housekeeping gene expression in different pathological states. Cemented and non-cemented replacements of the trapeziometacarpal joint. Influence of different parameters on reconstitution of lyophilized SLN. Recruitment mechanisms in speed and fine-direction discrimination tasks. This survey reveals considerable variation in the amount and pattern of immunosuppressive use in ulcerative colitis, with serious side-effects commonly seen.

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An experimental approach to the analysis of mechanisms of meiotic nondisjunction and anaphase lagging in primary oocytes. Both F419 and DI mutants display impaired ability to induce tyrosine phosphorylation of a series of cytoskeletal and cell-cell interacting proteins. The most recent surveys show that 30 per cent of male industrial workers and 20 per cent of male students have used drugs at some time in their lives, and, among them, approximately 25 per cent have continued to do so. Therefore, only cells that express OC also express TAg and are immortalized in vitro. Oxindole administration (1-100 mg/kg i.p.) to mammals decreases locomotor activity, reduces muscular tone and blood pressure and at larger doses causes coma and death. Cardiac remodelling is first an adaptive, becoming a maladaptive, compensatory mechanism that finally causes ventricular dysfunction independently of the etiology of the initial insult. Mechanics of ventilation in swellsharks, Cephaloscyllium ventriosum (Scyliorhinidae). The primary treatment for non-GERD-related noncardiac chest pain, regardless if oesophageal dysmotility is present, is pain modulators. Statistical analysis was performed by using the Friedman two-way analysis of variance and the Cochran Q test. While c-di-AMP binds to specific proteins that regulate pathways in bacterial cells, c-di-AMP also binds to regulatory RNA molecules that control potassium ion channel expression in Bacillus subtilis.

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Active remote technologies such as LiDAR operated from airborne platforms provide only partial crown reconstructions. Although considerable progress has been made identifying the targets for cell wall active antibiotics, little is known about the intracellular mechanisms that are activated as a consequence of cell wall injury. The magnitude of peak enhancement increased with the injection rate, but the increase was different in the aorta and liver. Meanwhile, the grooves between nanohemispheres will provide the extra driving force for DV stacking. The dominant interaction is with the repressor factor, chicken ovalbumin upstream promoter transcription factor. The effect of subvalvular apparatus preservation on the hemodynamic function of the heart in the early postoperative period after prosthetic mitral valve replacement. However, the HoLEP technique appeared to be a less invasive technique, reducing the duration of catheterization, blood loss, and the average length of stay while maintaining good efficacy for the enucleated prostate volume. A questionnaire identified those athletes currently suffering from such pain. Prostaglandin E2 Production and T Cell Function in Mouse Adenovirus Type 1 Infection following Allogeneic Bone Marrow Transplantation. Endoscopically, these lesions can easily be mistaken for malignant tumors.

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Evaluation of the histologic grade by EB and of the depth of myometrial invasion by intraoperative biopsy is a good option for deciding the necessity of lymphadenectomy. Pharmacokinetics, biliary excretion, and tissue distribution of novel anti-HIV agents, cosalane and dihydrocosalane, in Sprague-Dawley rats. Rapid determination of five coagulation parameters in one sample with a centrifugal analyzer. For a wide variety of conditions, patients are being implanted with active and passive devices or treated with advanced microsurgical instrumentation. Virus safety, purity and validity of blood and blood products are described as parameters of the quality aspects. The migration of highlanders to the city mainly affected their mortality and morbidity, but not fecundity.

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Calendar year patient cohorts (2005-2013) with breast, colorectal, lung, multiple myeloma, non-Hodgkin lymphoma, ovarian, or prostate cancer and receiving myelosuppressive chemotherapy were identified within the Marketscan database. We report that two members of the histone demethylase KDM4 family act as major regulators of AR transcriptional activityin EC. Each cell source has advantages, but also has technical hurdles to overcome, including heterogeneity, functional maturity, immunogenicity, and pathogenicity. Safety climate has been not yet mature in the hospital surveyed that might be partly tied with blame culture. High-Resolution Fourier Transform Infrared Spectroscopy of Nitrosyl Fluoride. Scanning laser ophthalmoscopy provides additional information for precise evaluation and follow-up of the retinal damage in BRVO. gonorrhoeae multiantigen sequence typing (NG-MAST) ST1407 isolates with the mosaic penicillin-binding protein (PBP) 2 XXXIV have accounted for most ESC resistance globally. Both, GSPET MPI and RNV seem to be underutilized in pediatric clinical practice due to increased radiation exposure.

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tuberculosis loci in ancient human remains and suggests important applications in the study of the palaeoepidemiology and virulence of tuberculosis in past populations. At potentials higher than 0.2 V, chlorobenzene binds to Pt via the Cl atom and can be converted to benzene (less than 0.3 V) or desorbed. Standard methods for hepatitis C virus (HCV) RNA quantification are time-consuming and often hampered by low sensitivity. Interaction of the N-Terminal Tandem Domains of hnRNP LL with the BCL2 Promoter i-Motif DNA Sequence. Visual and surgical outcomes of retinal detachment following macular hole repair. Simultaneous measurements of sagittal knee laxity with an external device and radiostereometric analysis. The C677T mutation of the methylenetetrahydrofolate reductase gene and the G1691A (Leiden) mutation of the factor V gene are established risk factors for thromboembolic disease.

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Intracranial esthesioneuroblastoma associated with unilateral visual loss. Overview of adverse effects of integrative medicine treatment of social communication stress on bronchial asthma. However, early implementation of treatment substantially improves the disease prognosis. Differences in the language spoken by residents and staff in long-term care create a variety of problems. Hemodynamic and pulmonary changes during and after laparoscopic cholecystectomy. This can be difficult due to the large processes that mark these glial cells. Hypothesis: prolactin is tumorigenic to human breast: dispelling the myth that prolactin-induced mammary tumors are rodent-specific. Incidence of hypotension and acute hypotensive transfusion reactions following platelet concentrate transfusions.

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This is the first evidence that HIV-1 may affect HCMV replication indirectly, via the interaction of gp120 with the monocyte membrane, in the complete absence of retroviral replication, through the stimulation of IL-8 release. Food allergy is increasing in frequency and so is the misunderstanding of what constitutes a true food allergy. Interestingly, substantial early weight loss was associated with sustained loss, suggesting a responsive phenotype and future trials might best be targeted in identifying responsive subpopulations. The results of suprathreshold speech recognition tasks show substantial variability in performance but this is no greater than that obtained from implant users with no malformation. Understanding for whom, under what conditions, and how group-based physical activity interventions are successful: a realist review. Effectiveness of Lymphatic Microsurgical Procedures in the Treatment of Primary Lymphedema. Efficacy and Safety of Apremilast in Patients With Moderate Plaque Psoriasis With Lower BSA: Week 16 Results from the UNVEIL Study. Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts. This brief review traces the origins of the group focussing on its more recent depakote dosage elderly history and reviewing some of its major contributions to lupus research during the past two decades.

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This delayed control allows a consistent neural implementation, i.e. The concept of interrelated disorders extends to the previously orphaned distal muscular dystrophies, or distal myopathies, as they are often called. Bradykinin and angiotensin II activation of arachidonic acid deacylation and prostaglandin E2 formation in rabbit kidney. Despite their relative infrequency (which is often used as an excuse for poor treatment), soft-tissue sarcomas have been the focus of considerable interest and advances in recent years, mainly because of molecular genetic developments as well as evolution in their histological classification. This indicates that transcription of beta globin gene takes place in Ferrara beta 0 thalassaemia. Our findings supported our hypothesis that high optimism mitigated the intergenerational transmission of high BMI, but only in women. Dynamic reconstruction of heterogeneous materials and microstructure evolution. In the six larger studies (more than 100 deceased patients) that used a continuous categorization of glycaemia, tenormin 25 mg tablet side effects the Risk ratio per unit varies from 1.03 to 1.12. Failure of anterior cruciate ligament reconstruction: the biologic basis.

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During an experimental anterior vitrectomy on aphakic rabbit eyes, corneas were perfused with a different solution in each eye during a period of up to 75 min and with a maximum of 250 cm3 of liquid. To improve precision of measurement, rules used by observers in processing tomograms were encoded for automation. Such clonally isolated cells overexpressing I kappa B alpha super-repressor not only were viable but also exhibited no sign of spontaneous apoptosis. At this same time, the optic tectum already received secondary visual afferents originating in the ipsilateral pretectum and non-visual afferents from the ipsilateral semicircular torus and tegmentum. The effect of glucocorticoids and heparin (in depot form) on the DNA-synthesis of thymus and spleen of mice was investigated by measuring (3H)dThd incorporation in a four day period. In the same rats, ACTH and corticosterone secretion was also stimulated by the stressor, but the hypothalamo-pituitary-adrenal (HPA) axis response was not attenuated in sex-steroid treated rats. Smoking is associated with hypermethylation of the APC 1A promoter in colorectal cancer: the ColoCare Study. Recognizing that PAD is considered a coronary artery disease risk equivalent emphasizes that primary care physicians and cardiologists need to be aggressive for screening and treatment of this disorder. The lungs are a common metastatic site for anaplastic thyroid cancer (ATC), and metastasis is one of the most frequent causes of mortality in this type of cancer.

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Structural analysis by MALDI- zantac medicine definition TOF MS indicated the increased proportion of mono-rhamnolipids from SSS fermentation. Mouse somatic mutation orthologous to MELAS A3302G mutation in the mitochondrial tRNA(Leu(UUR)) gene confers respiration defects. Importantly, we provided a guideline to construct libraries of frozen tissue with minimal effort, cost and space. Among them, members of the family of astacin-like metalloproteases were particularly abundant. The results of the present study may have important clinical implications since blockade of leukocyte migration can be achieved after topical application of NSAID.

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How cellular signals from CD31 and other adhesion amplifiers are integrated with those from classical mitogenic stimuli to regulate leukocyte function remains poorly understood. The self-assembly leads to the precise positioning of the QDs in QDs array where the inter QD distance is being maintained by the DNA sequence length. In two infants with pneumonia, Coombs test positive hemolytic anemia and hemolytic uremic syndrome (HUS), exposure of the Thomsen cryptantigen, probably due to the action of circulating neuraminidase, was demonstrated. Ten minutes after stopping CPB geometric means for cholesterol and triglyceride were 3.90 (0.82) and 0.90 (0.58) mmol/L, respectively. No other marked differences in plasma BAS between the responders and nonresponders to antihypertensive treatment were found. Mapping chromosomal homology between humans and the black-handed spider monkey by fluorescence in situ hybridization.

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The best-performing features in the univariable analysis were included in the multivariable analysis after the exclusion of redundant features. These parameters did not change in control patients during a similar time period. The effects of methadone on respiration and ventilation in Pygmy goats. Preoperatively, 32 had enlarged peritracheal nodes greater than 15 mm in diameter on computed tomography, 18 had hard unmobile tumors in the lower neck, 9 had recurrent laryngeal nerve palsy, and 10 had findings suggestive of tracheal invasion. Laparoscopic renal cyst decortication is an effective minimally invasive treatment for painful simple cysts. It is hypothesized that this situation is exquisitely suitable for studying the pathophysiology of severe inflammatory responses in humans. This RT-PCR product hybridized in Southern blot analysis with the oligonucleotide probe designed to the highly conservative beta2-AR region involved in G-proteins interaction and located within the amplified region. In 2- to 7-day chick embryos, we find that genes of the LIM homeobox family are expressed differentially among cranial motor nuclei.

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Relation of iodine-123 metaiodobenzylguanidine myocardial scintigraphy to endomyocardial biopsy findings in patients with dilated cardiomyopathy. The assumptions underlying a strong phonological theory of reading are outlined, and 4 theoretical questions are examined: Is phonological recoding a mandatory phase of print processing?. Versive or circling seizures may occur in the context of an IGE. Treatment of cMNC and aPBMC with interleukin-2 (IL-2), IL-12 or IL-15 significantly enhanced killing activity against K562 cells and CMV-uninfected and -infected cells. A coupled fiber-matrix numerical model was developed in this work for predicting the mechanical response of collagen scaffolds subjected to various levels of non-enzymatic glycation and collagen concentrations. These results suggest that the double-stapling technique is as safe as the single-stapling technique for constructing an anastomosis after excision of the rectum for cancer, in terms of the risk of leakage, the development of an anastomotic stricture, or local recurrence.

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Polarization contributions to intermolecular interactions revisited with fragment electric-field response functions. Responses of the gastric musculature of the sheep to some humoral agents and related substances. Low dose chlormethiazole infusion as a supplement to central neural blockade: blood concentrations and clinical effects. In contrast to STA, Con A binding elicits this reaction with involvement of diacylglycerol kinase, protein kinase C and/or calmodulin as well as thiol level perturbation, as inferred by the application of target-selective inhibitors. Comparison of synthetic serum substitute and fetal cord serum as media supplements for in vitro fertilization: a prospective, randomized study. We present data from the Korean National Health and Nutrition Examination Survey 2008-2009 on the distribution of blood cadmium levels and their association with iron deficiency in a representative sample of the adult Korean population. leprae sonicate antigens in regulating the expression of the costimulatory molecules B7-1, CD28, intercellular adhesion molecule-1 (ICAM-1), LFA-1alpha, LFA-1beta and Mac-1 on the lymphocytes of both leprosy patients and healthy subjects. Research projects in prevention have been rather limited, but we may draw two conclusions: To identify the risk children theolair 250 mg has not been the problem--the interventions must be rather comprehensive for counteracting the risk factors, rendering them harmless. A constraint in the development of laboratory animal models of human disease conditions is their applicability to the natural environment in which a given animal species evolved.

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Information support, illness perceptions, and distress in survivors of differentiated thyroid cancer. The relationship between olfaction and mortality, however, may be largely mediated by cognitive impairment in these older adults. Cost-effectiveness of the Family Nurse Partnership (FNP) programme in England: Evidence from the building blocks trial. The discovery and development of SU14813, a next-generation multitargeted tyrosine kinase inhibitor for the treatment of human malignancies. The results should be interpreted with caution due to potential biases. They express important lymph node homing receptors which were functional and induced chemotaxis of T cells in vitro. The Scnn1b gene was closely linked to the Sa gene on rat chromosome 1. Cross-sectional studies have reported inconsistent findings on whether the risk of metabolic syndrome is high among cancer survivors.

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The crystals were colorless or basophilic on the hematoxilin and eosin-stained section and could be visualized with polarized light as doubly fractile crystals. In 4 other patients, pulmonary vasodilator therapy with prostaglandin E1 and amrinone had failed and they were treated with inhaled nitric oxide (NO). This is the lowest phase noise level ever demonstrated by monolithically integrated OPLLs. Clinical implications of novel mutations in epigenetic modifiers in AML. Then, both groups received a test for conditioned reinforcement in which leverpresses resulted in the brief presentation of the stimulus previously paired with food. Rac and the related GTPase Cdc42 also regulate the dynamics of the actin cytoskeleton, necessary for leukocyte chemotaxis and phagocytosis of microorganisms. Examination was performed on NTG eyes with well-defined NFLD borders which were divided into the groups of with and without DH. Beam damage to organic material is considerably reduced in cryo-electron microscopy.

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We identified all TAA from January 2014 to December 2014 at the OSH and January 2010 to January 2016 at the ATH. Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit. These data suggest that the pattern of glomerular injury induced by a planted antigen can be determined by the balance of T helper cell subset activation. Within benign tissue, GST-pi immunostaining was distinguished between basal cells and secretory acinar epithelium. Repository corticotropin injection as adjunctive therapy in patients with rheumatoid arthritis who have failed previous therapies with at least three different modes of action. The mini-transposon and IS204 transposase gene were then put on a kanamycin-resistant conjugative plasmid pDZY101 that can only replicate in Escherichia coli. However, further research is required to define the supplementation period, the dose and the type of Ca supplement (milk or salt) required for more effective results. These studies demonstrate the therapeutic potential of cold weather masks in protecting asthmatics against the effects of exercise and cold air. The most commonly used tool for maxillo-mandibular fixation to the patient who underwent reconstruction using a vascularized bone graft after mandibular resection is a dental arch-bar.

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