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Alparazole (Alprazolam)
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Alparazole

Alparazole is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alparazole is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alparazole may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Acalm, Alcicalm, Alparazole, Alpose, Alpraday, Alprastan, Alproz, Alzopam, Anxit, Belfa, Cozac, Depoxit, Depten, Dexolam, Exprex, Fluzolam, Morecalm, Normatine, Pifzot, Proprazolam, Restam, Somaspas, Sozox, Trustin, Xerodep, Xylonite, Zallpam, Zeecam, Zolark, Zotam

Similar Products:
Ventolin, Nuvigil, Casodex, Prevacid, Glucotrol, Danocrine, Sovaldi, Clozaril, Ovuclom, Escidant, Farlutal, Neumoflox, Tryzo,

Also known as: Alprazolam

Description

Alparazole (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

Alparazole is used to treat anxiety disorders and anxiety caused by depression.

Alparazole is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase Alparazole on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.

Dosage

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Measure the liquid form of Alparazole with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not swallow the orally disintegrating tablets whole. Allow it to dissolve in your mouth without chewing.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

You may have seizures or withdrawal symptoms when you stop using Alparazole. Ask your doctor how to avoid withdrawal symptoms when you stop using Alparazole.

Keep track of the amount of medicine used from each new bottle. Alparazole is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alparazole XR dosage information

Side effects

The most common side effects associated with Alparazole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Alparazole if you are pregnant. It could harm the unborn baby.

Do not use this medication if you are allergic to Alparazole or to other benzodiazepines, such as chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).

Before you take Alparazole, tell your doctor if you have asthma or other breathing problems, glaucoma, kidney or liver disease, a history of alcoholism, or a history of depression, suicidal thoughts, or addiction to drugs or alcohol.

Do not drink alcohol while taking Alparazole. This medication can increase the effects of alcohol.

Alparazole may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.

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Detection of herpes simplex virus DNA in tear fluid of stromal herpetic keratitis patients by nested polymerase chain reaction. Differential pulse polarography and electron spin resonance spectroscopy of nitroxyl free radicals used as ESR-spin probes. Enhanced growth of the tested microorganisms at concentrations of antibiotics large enough to inhibit the growth of the S and M variants, but insufficient to suppress the R-variant, was shown to be determined by the intense development of the latter variant. We propose a model for the selection of restriction sites by type I enzymes where two EcoR124II complexes bind to two recognition sequences. This effect is not explained by an alteration in the ability of animals to respond to odorants or to execute motor programs. The QRS complex deformity of myocardial infarction in the human subject.

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We appeal to two widely-separated waves of Add Health data to map out the correlation between childhood sports and a number of adult labour-market outcomes. Independently predictive prognostic variables after resection for colorectal carcinoma. The structural results are discussed with respect to the production of a chemically complex (emulsion-like) adhesive, its controlled release to the exterior, and the micromechanical properties of the cuticle of the pliable pad. We presented a case of gallbladder cancer with EOPBD into the duodenal bulb. Study findings will be disseminated via presentations at national/international conferences and peer-reviewed journals. Reactive oxygen species (ROS) are important second messengers for the induction of several genes in a variety of physiological and pathological conditions. The purpose of this study was to determine whether a large size needle induces more pain compared to a smaller size needle for radial arterial puncture and to assess the anxiety associated with radial arterial punctures. Likewise, the reduction in Akt activity upon sIg-FcgammaRIIb co-clustering is absent from avian B cells lacking expression of SHIP.

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Our experience adds further support that CCAM can act as a premalignant lesion. That design was printed with polylactic acid on a commercially available 3D printer. The possible role of the selenium binding proteins (SBP) during Cd exposure are also evaluated. Both in vitro cytotoxicity and in vivo immunotoxicity assays give substantial evidence of excellent biocompatibility attained in the NAs. Recent observations of the matrix by TEM reveal complex fibril-delimited channels and capillary systems which partially traverse marine snow flocs and which are postulated to play roles in anomalous settling. Alteration of proteoglycan synthesis in human lung fibroblasts induced by interleukin-1beta and tumor necrosis factor-alpha. Psychometric properties of the Spanish version of the Adolescent Stress Questionnaire (ASQ-S). Positive HIV (human immunodeficiency virus) serology in the pregnant woman: current data on its management. Even if proper and timely medical response is achieved, however, the patient may still experience permanent neurologic sequelae or death.

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Histological study of healing of a laterally positioned flap: apropos of a case. Other potential surrogate end points that may occur earlier in carcinogenesis are being analyzed in these precancers and in nearby normal appearing tissues. Among these malignant transformations, urothelial cell carcinoma is rare. Recovery rate and quality of embryos from mares inseminated at the first post-partum oestrus. Cushing and other great neurosurgeons made their mental preparations for surgical procedures through extensive, beautiful drawings. Pathophysiology, clinical features and management of hepatorenal syndrome. The proposed classification schema provides a practical means to determine the emetogenic potential of individual chemotherapy agents and combination regimens during the 24 hours after administration. Ultrafast Terahertz Gating of the Polarization and Giant Nonlinear Optical Response in BiFeO3 Thin Films. Mucous and oxynticopeptic cells in the gastric mucosa of the seps, Chalcides chalcides (Linnaeus, 1758) were examined by standard histochemical staining methods and by lectin histochemistry. We identified polymorphisms in the gene (ropB) encoding the RopB regulator that associate with altered transcription of speB and production of the SpeB protein, a critical secreted protease virulence factor.

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This change is partly explained by the social processes that constitute a significant factor in the etiology of the disease. On the whole, however, the reconstruction of defect through local tissue transfer is still considered as the treatment of choice. Malignant mesothelioma due to environmental exposure to erionite: follow-up of a Turkish emigrant cohort. Introduction of AFT1(up), a constitutive allele of the iron transcription factor, AFT1, that also leads to increased high affinity iron transport did not prevent Deltayfh1 cells from becoming respiratory-incompetent. We have been investigating the molecular basis of esophageal carcinogenesis in an attempt to develop gene therapy of established esophageal cancers and premalignant esophageal lesions. Stasis dermatitis is a cutaneous finding associated with chronic venous failure resulting in venous stasis. Outcomes of interest were pain, adverse effects, function and quality of life.

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The control group had amalgam restorations in contact with the oral mucosa but without any reactions. Acute leukemia treated with ACTH and cortisone: temporary remission, development of tumoral splenomegaly, relapse and death. FGR mice can present with delayed puberty with rare ovulation and adulthood insulin resistance, and high-fat feeding after birth can promote the catch-up growth of FGR mice. Since the first description of percutaneous dilatation tracheostomy (DTT), it has become an alternative method of equal value to surgical tracheostomy. The NMDA receptor/ion channel blocker, dizocilpine, induced a deficit in spontaneous alteration, but when ifenprodil was co-administered with dizocilpine, it showed a strong tendency to attenuate the dizocilpine-induced deficit. Thirteen pregnane glycosides were isolated from fresh leaves of Marsdenia tomentosa collected in the Fukuyama district. Pluripotent embryonic stem (ES) cells can generate all cell types, but how cell lineages are initially specified and maintained during development remains largely unknown. Analytical formulas for signal loss due to diffusion in the pulsed gradient spin echo (PGSE) experiment for this tissue model are derived.

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Tumor necrosis factor-induced apoptosis stimulates p53 accumulation and p21WAF1 proteolysis in ME-180 cells. The plants were first irradiated with Co60 source (0, 10, and 25 kGy) and then subjected to Clevenger extraction to obtain essential oils. Mice were treated with 20, 100 and 500 mg/kg acamprosate for 21 days. Carboplatin can be safely delivered intracranially by biodegradable sustained- release polymers. The VGPS was developed using standardized and cross-culturally validated metrics, including the Brief Pain Inventory and World Health Organization Disability Assessment Scale, as well as the Pain Catastrophizing Scale, the Fibromyalgia Survey Questionnaire along with queries about pain attitudes to assess the prevalence of chronic pain and disability along with its psychosocial and emotional associations. 327 Borrelia isolates from ixodid ticks of 3 species from 12 major administrative territories of Russia (from Leningrad Province in the west to Sakhalin Province in the east), as well as from forest myomorph rodents of 6 species and from skin biopsies of borreliosis patents, were identified by the PRC and RFLP methods. The Metacarpal Locked Intramedullary Nail: Comparative Biomechanical Evaluation of New Implant Design for Metacarpal Fractures.

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In L1210 cells 3a is converted to 8-aminoinosine monophosphate (4b), apparently by the action of AMP deaminase on the monophosphate of 3a, as well as to the triphosphate derivative of 3a. Participants were classified into four repressive coping groups according to the Taylor Manifest Anxiety scale and the Marlowe-Crowne Social Desirability scale. acidophilus CRL 730, are used in a commercial fermented milk (BIO MILK), which is believed to be beneficial for health. Effect of temperature on FAD and NADH-derived signals and neurometabolic coupling in the mouse auditory and motor cortex. This expression, which occurs in the absence of stress, is then repressed. Branchial abnormalities occur when there is disturbance in the maturation of the branchial apparatus during fetal development. Results were compiled and reported according to the Clinical and Laboratory Standards Institute Analysis and Presentation of Cumulative Antimicrobial Susceptibility Test Data. Endometriosis is an estrogen-dependent chronic inflammatory condition that affects women in their reproductive period. These methods are random amplification of polymorphic DNA (RAPD), amplified fragment length polymorphism (AFLP) and high resolution melting (HRM). There is recent and widespread interest in the damage-associated molecular pattern molecules S100A8 and S100A9 in cardiovascular science.

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OSHA and NIOSH conclude that 2-nitropropane (2-NP) is a confirmed carcinogen in laboratory rats. The author argues for urgency in the pursuit of a dialogue that examines varied definitions of harm and risk for children, and the implications of those definitions for cultural conflict, screening and intake, and resource allocation. Since then, more than 750 articles related to their phytochemical analysis have been published. Three exercise modes were identified including: isolated muscle training, instability training, and general strength training. Neurochemical and peptidergic pathways of the baroreflex arc in the medulla oblongata: an introduction. Minimal secondary structures of the bacterial and plastid tmRNAs were derived by comparative analyses of 50 aligned tmRNA sequences.

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In the yeast Saccharomyces ceresivisiae, the essential gene CSE1 encodes a Cas homologue that exports the yeast importin-alpha protein Srp1p/Kap60p from the nucleus. Ginsenoside 20(S)-Rh2 has been shown to induce apoptosis and differentiation of acute myeloid leukemia (AML) cells. The metabolism of chromosomal proteins has been studied in the pancreas, liver, and kidney of adult mice (a) by measuring the rates of glycine-N(15) incorporation into histones and residual chromosome fractions, and (b) by zebeta dosage measuring the extent to which N(15), once incorporated into chromosomal proteins, is retained. Comparison with other French or European experiences at the time of preparation of this report, presented to the 97th French Surgery Congress in 1990, allows the definition of a consensual management. Mutation in CEP63 co-segregating with developmental dyslexia in a Swedish family.

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Although BME analysis is complex, the clinical significance for allo-BMT patients warrants the effort to develop, validate, and perform BME analysis in support of the allo-BMT service. attenuation of symptoms and a decrease of the intramuscular pressure, especially after exercise. Moreover, in nontransgenic mice, therapeutic administration of hsp60 or hsp60 peptides, known to modulate naturally occurring hsp60 autoimmunity, led to delayed allograft rejection. The recovery of latent text from thermal paper using a simple iodine treatment procedure. The advocacy for tobacco control by the civil society and community led initiatives has acted in synergy with tobacco control policies of the Government. Community airborne particulate matter from mining for sand used as hydraulic fracturing proppant. For the remaining 8 percent of patients, operated on for worsening symptoms, the carcinoma was detected in the pathological specimen only.

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A refluxogenic meal was given during the course of the recording to induce reflux in the subjects. TEWL measurements indicated that the application of the vegetable oils (except jojoba oil) as well as paraffin oil, led to a similar occlusion of the skin surface. This report presents 2 cases: the first demonstrating a 5-cm pseudoaneurysm of the right internal mammary artery and the second demonstrating a 2.3-cm aneurysm of the left internal mammary artery, each following aortic root surgery. They felt proud working with mothers and babies and shared their frustrations having to deal with inadequate working conditions. The most current guidelines classify based on clinical features at initial presentation and are used to both risk stratify and guide the management of haemodynamic compromise. Effects of substances on both the incidence of arrhythmias during ischemia and the reperfusion period and mortality were investigated in the rat model ischemia-reperfusion injury. We conclude that rapid intra-atrial infusion of procainamide is very effective in this animal model of PAF, and that such infusion prolongs atrial MAP, ERP and CT. MR imaging (0.3 T) was first performed before and after Gd-DTPA at 0.1 mmol/kg b.w., and then within one month (17 patients) or within 3 months (3 patients) before and after gadodiamide injection at 0.3 mmol/kg b.w.

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Two-thirds of the operatively treated but only one-quarter of the non-operatively treated patients were able to walk alone when they left hospital. To evaluate the various reconstruction methods of helical-CT angiography for the assessment of hemodynamically relevant renal artery stenoses in comparison to i.a. Concurrent and noncontiguous squamous and transitional cell carcinomas of a bladder. Electrochemical DNA biosensor based on a glassy carbon electrode modified with gold nanoparticles and graphene for sensitive determination of Klebsiella pneumoniae carbapenemase. Antibody against c-myc precipitated Res-FLAG from detergent extracts of cells expressing both forms, but not when Res-FLAG was expressed alone. No differences in symptoms were found among subjects with higher versus lower levels of Psychoticism. After wounding, APLP2 mRNA and polypeptides were increased markedly in the basal epithelial cells that were actively migrating. Aureomycin in therapy of vaginitis caused by Trichomonas vaginalis.

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Single-Stage Reconstruction of Eyebrow Defect Using a V-Y Advancement Pedicle Flap Based on the Orbicularis Oculi Muscle. Subcutaneous indomethacin suppressed the first phase of fever produced by high concentration of intravenous endotoxin or endogenous pyrogen, but not the second phase. When cytosine arabinoside was added to cells with or without stimulation by HGFs, the viable G0-phase cell count was reduced in HGF-stimulated cells compared with unstimulated cells in seven of eight cases. There was no predilection for coherence within a given frequency band to be associated with cortical sites that had been functionally defined as producing contralateral arm motor responses on stimulation. The influence of the additional mass and stiffness provided by the attached piezoelectric devices on the wave propagation characteristics of the structure is also investigated.

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Activated Tissue-Resident Mesenchymal Stromal Cells Regulate Natural Killer Cell Immune and Tissue-Regenerative Function. The selection and preservation of specimens to be forwarded to diagnostic laboratories for assistance in confirming the tentative diagnosis are of critical importance in gaining the maximum information from a necropsy examination. As a single stabilizing feature, truncation appeared more effective in locating a lens in the correct meridian than prism ballasting. Resequencing of SLCO2A1 revealed a nonsynonymous variant, rs34550074 (p.A396T), and association with this SNP was replicated in a second cohort of TIH cases. Growth factor modulation of mitogenic responses and proteoglycan synthesis by human periodontal fibroblasts. Shikonin was selected as index, optimized chromatographic condition was used for analyzing the affection of alcohol content and crude drug content of sample solution on determination of shikonin, furthermore, reasonable sample preparation and determination methodology was examined and defined.

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An increase of alcohol dehydrogenase activity is observed in patients with chronic alcoholism at the first stage of the disease under normal indices of activity of aldehyde dehydrogenase, aspartate- and alanine aminotransferase and thymol sample that evidences for the induction of alcohol dehydrogenase synthesis in the liver. Morphological analysis of malignancy: a comparative study of transplanted brain tumours. Further, the effectiveness and modality of prolonged antibiotic prophylaxis and/or preoperative respiratory physiotherapy should be assessed in such cases. The characteristics of the use and the levels of diffusion of nonconventional medicine. It appears that a higher ketamine concentration at the receptor site was required in the rat as compared to man. We hypothesized that plasma DNA is increased in patients with trauma and may be prognostic in such patients. We established rat models to evaluate the effect of gastric acid hypersecretion on gastric emptying and the GD-induced pain response. After life-day 30, large infarct-like lesions predominantly located in the central portion of the left ventricular walls were observed, while single cell necrosis occurred only in a few cases. Though the solvent produces an important decrease in the stability of the complexes, the results suggest the possibility of employing these substituted buckybowls as anion receptors with a preferential concave complexation, especially for large anions. PCR in laboratory diagnosis of human Borrelia burgdorferi infections.

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