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Almee (Alprazolam)

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Almee is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Almee, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Almee is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alcicalm, Aleez, Alprac, Alpraquil, Alprasert, Alprosym, Alsert, Alzam, Alzoax, Axizox, Azicalm, Benzolam, Endep, Fluxozam, Fluzolam, Golprax, Isorest, Mebasap, Mebaspa, Mentolift, Norex, Plxna, Poize, Prazil, Prazolam, Restam, Restyl, Rezolam, Serxanti, Sinaday, Sinzolam, Somnia, Tranax, Tranisol, Trazopin, Trika, Xycalm, Zallpam, Zedep, Zeftra, Zenax, Ziety, Zoldac, Zolipax, Zomark, Zorest

Similar Products:
Clozaril, Prograf, Ceftin, Mestinon, Zyprexa, Singulair, Rebetol, Evista, Viroxit, Amlovas, Zefu, Floximax, Albekon, Diaser,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Almee XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Almee are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

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A classification system that enables healthcare professionals to anticipate and describe failures following the index procedure, thereby impacting the choice of options for retreatment, may facilitate consistency and standardization within the heterogeneous field of endovascular device treatments for the femoropopliteal artery. Furthermore, we analyzed the MoAb34:EPO-R interaction using a mathematic model describing antibody-mediated receptor dimerization. Scleral contact lenses provide unique therapeutic and vision rehabilitative properties that overcome the therapeutic gaps encountered with conventional contact lens therapies. In this study, we identify a new function of neuritin as a novel angiogenic factor in vitro and in vivo. Expression and characterisation of Plasmodium falciparum acidic basic repeat antigen expressed in Escherichia coli. Can we reliably predict the development of hospital acquired infections after septic shock?. Understanding the relationship between PNPLA3, NAFLD and insulin resistance: do ethnic differences bring more questions or more answers?. Consciously over Unconsciously Perceived Rewards Facilitate Self-face Processing: An ERP Study. We discuss the case in detail and comment on the concept of stigmata in general.

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OH 83: A new early modern human fossil cranium from the Ndutu beds of Olduvai Gorge, Tanzania. Identification of the hematopoietic growth factors elaborated by bone marrow stromal cells using antibody neutralization analysis. Nedocromil sodium: a review of the evidence for a dual mechanism of action. The NTP and PHS need better collaboration to improve TB control in Malawian prisons. In the characteristics curve analysis of serum miR-124 for differentiating TEN patients from normal subjects, the area under curve was 0.94. Interleukin-2 was measured by the tritium-labelled thymidine CTLL assay on the supernatants of peripheral blood lymphocytes of gastric cancer patients after 24 hours stimulation with phytohemagglutinin. After randomization, 40 postmenopausal women without previous or current vasomotor symptoms were treated transdermally with either 50 micrograms/day 17 beta-estradiol or placebo during 14 weeks.

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The relationship between changes in proteinuria and myocardial infarction (MI) remains unclear in people with diabetes or pre-diabetes. AC fistula, large 3 cm in diameter, was on the posterior aneurysmal wall, and it connected the inferior vena cava and the left common iliac vein with AAA. This paper describes the introduction of a home-visiting service by district nursing staff, supported by a cardiac rehabilitation nurse specialist. These results suggest that HIV in the semen and blood compartments are distinct, and further, may respond differently to antiviral therapy. None of these women had had gonorrhea before or had a previous abortion. After needle biopsy confirmed a benign tumor arising from the smooth muscle, the tumor was removed by a transvaginal approach.

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Human alpha lymphotoxin (LT): studies examining the mechanism(s) of LT-induced inflammation and tumor destruction in vivo. Operation must be performed: in patients with postinfarction VSD or mitral insufficiency, with unstable angina and left mainstem stenosis, evolving infarction after PTCA. The relationship between postdefibrillation ventricular arrhythmias and shock strength is poorly understood in patients with implantable defibrillators. Mirror-image intracerebral hemorrhages in a patient with systemic lupus erythematosus. Ultrastructurally, irregularly distributed electron-dense deposits, occasionally assuming a concentric laminar appearance, were observed.

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This paper is proposing some possible future developments and further discusses on the security issues involved with such countrywide medical information system. Brachytherapy optimal planning with application to intravascular radiation therapy. However, these same patients often have contraindications to contrast-enhanced computed tomography and magnetic resonance imaging. The effect of mouse epidermal growth factor (EGF) was investigated on DNA and protein synthesis, progesterone and inhibin production by bovine antral granulosa cells. To determine which of these models is correct it will be necessary to find out whether transgene methylation, which is frequently associated with the potential of transgenes to confer post-transcriptional gene silencing, is a cause or a consequence of the process. In the adjusted model, the financially oriented behaviors had the strongest associations with gambling. Here, we examined three stained spinal interneurons receiving monosynaptic excitation from the SC.

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Maternal systolic blood pressure and urinary albumin were increased, while both fetus and placenta were restricted after GC exposure relative to the control group. Merkel cell carcinoma is an uncommon but highly immunogenic skin malignancy that has the potential to metastasize to any site in the body. The primary antiserum used in this study was a polyclonal antibody against DADTI previously used in adult and postnatal rat brain mapping. We conclude that it is possible to achieve perceptual and motor transparency in virtual one-dimensional remote needle insertion task. This study included 251 patients with vertical growth phase (VGP) primary cutaneous melanomas who had paraffin-fixed lesional tissue and were in a prospective cohort seen between 1972 and 1991, had no clinical evidence of regional nodal disease at diagnosis, and had at least ten years of follow-up. Between April 1996 and December 1997, 114 patients with periampullary adenocarcinoma were enrolled in an ongoing, prospective, randomized trial at The Johns Hopkins Hospital.

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Unique intranuclear filament inclusions in skeletal muscle fibers are its morphological hallmark. Although vaginal hysterectomy corrected the obstruction the development of post-obstruction atrophy was associated with hypertension and moderate renal failure. She had recurrent streptococcal tonsillitis, while the boy remained healthy in the throat. The potential cost-effectiveness of tailored communications must also be examined. Enantioselective Rhodium(I) Donor Carbenoid-Mediated Cascade Triggered by a Base-Free Decomposition of Arylsulfonyl Hydrazones.

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To describe psychosocial characteristics of children and young adolescents who experienced the recent suicidal death of a parent or sibling. To evaluate the membrane events that take place during red blood cell shape change, the deformability of resealed ghosts was studied in the ektacytometer while alterations in ghost shapes were produced. Ligation of the LSA after strict evaluation of collateral circulation could be safe for type A dissection patients if the exposure is insufficient, and this method can simplify the operation significantly. Lymphocytic panniculitis was observed in early biopsy specimens of all four cases, with focal histiocytic granulomas in one case. Sensory neuropeptides participate not only in nociception but also stimulate immune cells to release cytokines. A pattern of circular islands of adhesive substratum can be used to control cell shape and behaviour. Reciprocal skin grafting among syngeneic young and old animals further demonstrates autonomous aging of this organ independent of the remainder of the body. If the physical examination yields positive results, then magnetic resonance imaging followed by arthroscopic treatment was performed. Elimination of redundant synaptic inputs in the absence of synaptic strengthening.

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Asbestos: Social Legal and Scientific Controversies and Unsound Science in the Context with the Worldwide Asbestos Tragedy - Lessions to be Learned. I herein review these studies and their implications for the origin of antinuclear autoantibodies. A stereotaxic method of anatomical localization by means of H(2)15O positron emission tomography applicable to the brain activation study in cats: registration of images of cerebral blood flow to brain atlas. Effect of adrenocorticotropic hormone fragments and atriopeptides on the development of toxic brain edema-swelling. The involvement of the corticotropin-releasing hormone (CRH) type 1 receptor in CRH-induced cardiac responses was studied in freely moving rats. Volatile organic compounds (VOCs) from soil bacteria are likely to have an important role in the interactions among soil microorganisms. Nor was there any correlation to previous neuroleptic treatment: a pathological ABR was recorded in 5 of the 8 patients who had never received such medication. The demand for using nanostructures fabricated by focused ion beam (FIB) on delicate substrates or as building blocks for complex devices motivates the development of protocols that allow FIB-fabricated nanostructures to be transferred from the original substrate to the desired target. Bone mineral density was measured by dual-energy x-ray absorptiometry.

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Behavioral and pharmacological treatment of obsessive-compulsive disorders. We conclude that this difference is caused by a change in sensitivity, with higher sensitivities at night. Collectively, our analysis shows that the bead-free platform is a low-cost alternative that can be used by core facilities and other investigators to identify plant and viral proteins interacting with virions and/or the viral structural proteins. We compared rabeprazole, lansoprazole, and ranitidine for reduction of preoperative gastric fluid acidity and volume in elective surgery and found that a combination of bedtime and morning doses of rabeprazole, or a morning dose of ranitidine, similarly minimized the variables. In response to an increased flow of fatty acids, the liver will increase its production of VLDL particles yielding the phenotype of hyperapoB. Prednisolone at anti-inflammatory or immunosuppressive dosages in conjunction with doxycycline does not potentiate the severity of Rickettsia rickettsii infection in dogs. The SPECT ligand AM 281, a less lipophilic analog of the cannabinoid receptor antagonist SR 141716A, robustly potentiated electrically-evoked release of acetylcholine from superfused hippocampal slices and prevented the inhibition of acetylcholine release by the cannabimimetic drug WIN 55212-2. These findings support using the same management principles for patients with CT-only pneumonia and those with pneumonia seen on chest radiography.

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Varying amounts of type I collagen were added during the preparation of the DCP-rich CPC. Exciting work is underway in an effort to allow the electrophysiologist to assess scar formation in real time. Four upregulated (BUB1B, CCND2, CENPF, and MAD2L1) and two downregulated (LTF and SLPI) genes were markedly reported in six studies. Positive LTT was observed in 3/6 cases of mild eruptions, 1/9 SJS/TEN-cases tested during the acute phase and 3/14 SJS/TEN-cases tested after recovery. The ABO blood groups were determined in 125 patients suffering from venous thrombosis in a Brazilian population. Mean clearances increased significantly from 12.9 to 25.4 ml/min (P less than 0.01).

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The different granzymes have one of four primary substrate specificities: tryptase (cleaving after Arg or Lys), Asp-ase (cleaving after Asp), Met-ase (cleaving after Met or Leu), and chymase (cleaving after Phe, Tyr, or Trp). The window of opportunity for neuronal rescue with insulin-like growth factor-1 after hypoxia-ischemia in rats is critically modulated by cerebral temperature during recovery. Contribution of maternal and neonatal factors to the evaluation of umbilical cord blood. One aspect of the problem--relation between mortality and urbanisation (localities size)--is not the same with the sexes. Copyright 1998 European Federation of Chapters of the International Association for the Study of Pain. The effective attenuation coefficient of soft tissue in the presence of Compton scattering from bone: experiments on models. A commercially available transrectal ultrasound unit was coupled with a custom designed software system to construct 3-dimensional prostate images.

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Prolonged release from PLGA/HAp scaffolds containing drug-loaded PLGA/gelatin composite microspheres. Expression and degradation of the CYS3 protein are precisely regulated in a sulfur-dependent manner. Many countries, including high-income countries benefit from remittances from migrating individuals. In some subjects, this change occurs preceding and during movement, before changes in low or high frequency power. Sequencing revealed in-frame fusions consisting of part of BCR exon e8 spliced to ABL exon a2 in one patient and part of BCR exon e13 spliced to ABL exon a2 in the other. This study was designed to prove the hypothesis that local overproduction of interleukin-8 (IL-8) induces inflammatory cell accumulation which leads to the induction of REPE. Bad relationships with brothers and sisters and partners in their lives were related to current severe employment/support problems, and bad relationships with partners in their lives were related to current severe family/social problems. Radiotherapy Alone for Moderately Advanced Laryngeal Cancer (T2-T3).

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To ensure maximum diversity, the final library consisted of three sub-libraries. Many patients undergoing elective surgery will be taking medicines for cardiovascular disorders. In contrast, treatment with protein kinase C (PKC) inhibitor (bisindolylmaleimide) inhibited AEF-induced SC proliferation, but did not immediately affect CREB phosphorylation. Marine reserves solve an important bycatch problem in fisheries. Logic gates performing INHIBITION and YES/OR were constructed using surface-enhanced Raman scattering as optical outputs for the first time. However, this region is not overtly segmented in amphioxus, raising the question of how hindbrain segmentation arose in chordate evolution. Our study confirms an overall favorable prognosis in young patients with MF. Numerous cytoplasmic vacuoles, Golgi apparatus, vesicles and tubule-like structures were strongly labelled in the cerebral endothelia in the early stages of development but only sparse vacuoles and vesicles remained lectin-stained in the mature cerebral endothelia. The acquisition of Pseudomonas aeruginosa in the airways of patients with cystic fibrosis (CF) is the initial event leading to bronchiectasis and lung disease. The results suggest that the supramolecular ordering (short-range order) of crystallins is not a necessary condition for lens transparency.

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Comparison between valvular repair and replacement in severe mitral regurgitation. The resulting expressed protein glucophage xl dosage has been purified to homogeneity using a novel single-day chromatographic regime. The evidence presented here suggests that impacted mandibular third molars, which have not been infected, may be more likely to remain compared with other teeth at potential risk. The aims of the present study were to examine the effects of intravesical instillation of epirubicin on tumor recurrence and to identify tumors that are at a high risk of recurrence. Pattern A, achievement striving, and scientific merit: does pattern A help or hinder?. Monocytes produce a factor(s) that, in a second step, leads to bioassayable levels of CSF in the supernatant of adherent cells in LTBMC. However, integrin subunits and several cytoskeletal linker proteins, including vinculin, talin, and paxillin, showed an isoform-specific arrangement into focal adhesions.

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Expression pattern was determined by reverse transcriptase PCR, which showed all paralogous genes have distinct expression patterns, suggesting that they had undergone functional divergence. Children infected with human immunodeficiency virus (HIV) have had high rates of mortality attributable to measles, but until recently, measles vaccine was assumed to be safe for these children. The breakdown of myelin could impair cognition by leading to a change in the conduction rates along axons, resulting in a loss of synchrony in cortical neuronal circuits. The aim of this study was to investigate the influence of LR on morbidity and mortality in octogenarians. In order to define the cis -acting element(s) of ribosomal protein genes sensitive to a defect in the secretory pathway, we have constructed a series of fusion genes containing the CYH2 promoter region, with various deletions, fused to lacZ. Glucose starvation reduces IGF-I mRNA in tumor cells: evidence for an effect on mRNA stability. While different variables may influence the rate of VBAC, the predictive ability of VBAC for women with no previous vaginal deliveries remains poor.

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This action was blocked by nicotinic but not muscarinic antagonists. Induced Pluripotent Stem Cells-Derived Mesenchymal Stem Cells Attenuate Cigarette Smoke-Induced Cardiac Remodeling and Dysfunction. Reactive lymphoid hyperplasia celexa and alcohol side effects of the ocular surface: clinicopathologic features and search for infectious agents. The lived experience of Cauda Equina Syndrome: a qualitative analysis. Co-expression with WT SLC4A11 partially rescued the cell surface trafficking of CHED2 mutants, but not FECD mutants. Blood-brain barrier disruption was observed on contrast-enhanced MRI in the lesions and in a surrounding region corresponding to the prefocal area of the FUS system.

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The effect of estradiol was examined on the random and directional migration of different ER-positive ovarian-cancer cell lines. We have recently identified somatic hotspot mutations in RNase IIIb domain of DICER1 in half of ovarian Sertoli-Leydig cell tumors, a rare class of sex-cord stromal cell tumors in young women. There has not been an established method to distinguish initial lymphatics from blood capillaries under the light microscopy. The authors have shown that control cholangiography and especially choledochoscopy can reduce the danger to leave the stones in the ducts, but does not eliminate the danger completely. Skin prick testing with histamine and codeine phosphate did not show evidence of abnormal tissue reactivity or mast cell reactivity. However, specific, IgM type immunoglobulins produced against the erythrocytes decreased the intramembrane viscosity of cells. Following this latter premise, IS1358 elements from a variety of V. Exogenous expression and subsequent failure to down-regulate c-myc protein expression in SKBr3 and LNCaP cells was correlated with acquisition of resistance to the growth inhibitory effect of PMA.

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