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Aldezol (Metronidazole)
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Aldezol

Aldezol is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Other names for this medication:
Aldezole, Amebidal, Anaeromet, Clont, Colpofilin, Dazotron, Flagemed, Flagicure, Flazole, Flegyl, Ginkan, Klion, Klont, Lindoplus, Medamet, Metrajil, Metrobac, Metrodal, Metrolag, Metropast, Metrosa, Metroson, Metrozine, Micogyl, Nidazea, Nidazyl, Orogyl, Padet, Protozol, Rodogyl, Servizol, Trichazole, Trichostatic, Tricofin, Trikozol, Vagimid

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Also known as: Metronidazole

Description

Metronidazole is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Aldezol. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine is to be used only in the vagina. Use it at bedtime, unless your doctor tells you otherwise.

Do not get it into your eyes, nose, mouth, or skin. If this medicine does get into your eyes, wash them out right away with large amounts of cool tap water. If your eyes still burn or are painful, check with your doctor.

This medicine comes with a patient information leaflet and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Wash your hands with soap and water before and after using this medicine.

Nuvessa™ is available inside a prefilled applicator. The applicator is open at one end where you will insert the plunger and has a pink cap on the other end where the medicine will come out.

Vandazole® is in a tube. You will use an applicator to put the gel into your vagina. The applicator has a plastic tube called a barrel that is open at one end and has a plunger (another piece of plastic that can move inside the barrel) at the other end.

To use the medicine:

To fill the applicator: For cream or gel dosage forms: Nuvessa™: With the pink cap still on, push the tip of the plunger into the open end of the prefilled applicator. Pull the cap off before you insert the applicator into your vagina. Vandazole®: Break the metal seal at the opening of the tube by using the point on the top of the cap. Screw the applicator onto the tube. Squeeze the medicine into the applicator slowly until it is full. Remove the applicator from the tube. Replace the cap on the tube. For vaginal tablet dosage form: Place the vaginal tablet into the applicator. Wet the vaginal tablet with water for a few seconds. To insert vaginal metronidazole using the applicator: For all dosage forms: Relax while lying on your back with your knees bent (or in any position that you feel comfortable). Hold the full applicator in one hand. Insert it slowly into the vagina. Stop before it becomes uncomfortable. Slowly press the plunger until it stops. Withdraw the applicator. The medicine will be left behind in the vagina. Remove the applicator from your vagina. Use each applicator only once, and then throw it away.

To help clear up your infection completely, it is very important that you keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses. Also, continue using this medicine even if your menstrual period starts during the time of treatment.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For bacterial vaginal infections: For vaginal dosage form (cream): Adults—One applicatorful (500 milligrams [mg]), inserted into the vagina. Use the medicine 1 or 2 times a day for 10 or 20 days. Children—Use and dose must be determined by your doctor. For vaginal dosage form (gel): Nuvessa™: Adults and children 12 years of age and older—One applicatorful (5 grams [g]) inserted into the vagina once (at bedtime). Each applicatorful of Nuvessa™ contains 65 mg of metronidazole. Children younger than 12 years of age—Use and dose must be determined by your doctor. Vandazole®: Adults—One applicatorful (5 grams [g]) inserted into the vagina once a day (at bedtime) for 5 days. Each applicatorful of Vandazole® contains 37.5 mg of metronidazole. Children—Use and dose must be determined by your doctor. For vaginal dosage form (tablets): Adults—One 500 milligram (mg) tablet, inserted high into the vagina. Use the medicine once a day in the evening for 10 or 20 days. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Aldezol and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Aldezol overdosage: dizziness, seizures, torpor, retching, nausea, lack of balance, problems with coordination, tingling.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Metronidazole topical dosage information

Side effects

The most common side effects associated with Aldezol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Smartphones and tablets are new handheld devices always connected to an information source and capable of providing instant updates, they allow doctors to access the most updated information and provide decision support at the point of care. We evaluated normal blood glucose levels in two species of monkeys, namely rhesus monkeys (Macaca mulatta) and cynomolgus macaques (Macaca fascicularis) kept in the Breeding Center of the Institute of Medical Primatology. We take advantage of the copula paradigm, which makes it possible to separate dependence structure from marginal behavior. Problems were expected with coordination because there was not yet a structural reimbursement for such an activity for the frail elderly. The studies that developed and validated the rule used the identical manipulation procedure. To report contrast-enhanced sonography (CEUS) for solitary necrotic nodule (SNN) of the liver and to assess its clinical value. Here, we take a systematic approach and focus on the dynamic interactions that the stroma engages with the epithelium during mammary specification, cell differentiation, and branching morphogenesis of both the embryonic and postnatal development of the mammary gland. Furthermore, in binary variants, Mendelian inheritance errors are not randomly distributed.

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To overcome this, much effort has been dedicated to preparing transgenic pigs by knocking out Galalpha(1-3)Gal expression in these animals, or knocking in the expression of human complement regulatory proteins (CRPs), such as CD59 or decay accelerating factor. Our data indicate that in vitro priming of MSCs causes chromatin remodeling at the IDO1 promoter, that this alteration is maintained during processing commonly used to prepare MSCs for clinical use and that, once primed, MSCs are poised for IDO1 expression even in the absence of cytokines. Participants were recruited from 11 family practices in the east of the Netherlands and frail older people over 70 years. The most useful procedures are collected paying special attention to the synthetic application of this methodology in synthetic organic chemistry. These results indicate that the fully automated Web-based KNW provides personal relevant and valuable information and support for early cancer survivors. In particular, the integration of adolescent sexual partners into both family and friend networks is related to the expression of adolescent sexual behavior.

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The presence of a concurrent diagnosis of BN among women with BPD is significantly and uniquely associated with recent suicidal ideation, and self-harm behavior and suicide attempts during treatment after controlling for major classes of mental disorders. Extramedullary myeloma spread triggered by surgical procedures: an emerging entity?. Carotid intima-media thickness was evaluated using high-resolution B-mode ultrasonography. We use terrestrial carnivores as an example taxon, as they are frequently threatened or of economic importance. CBCT is useful in endodontics as it aids in the identification of essential anatomic structures and determination of radius and angle of root canal curvature which is linked to fracture of the instrument. Moreover, JunB overexpression induces osteoblast differentiation, shown by higher expression of osteoblast markers, and JunB knock-down not only decreases osteoblast differentiation but also restores the osteogenic potential to wild-type level in Smurf1(-/-) cells. monocytogenes serotype 4b, as demonstrated by immunofluorescence microscopy and immunogold transmission electron microscopy. Examine how different dosing schedules and recent stimulant therapy effect incidence, time to onset, and duration of common treatment-emergent adverse events (TEAEs) during atomoxetine treatment. The influence of the chain length and the molecular weight distribution of the electroluminescent polymer on the carrier transport properties and morphology of air stable hybrid light-emitting diodes is reported. The density and spatial arrangement of the invasive oyster Crassostrea gigas determines its impact on settlement of native oyster larvae.

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C-terminal fragments from the precursor for gastrin-releasing peptide (GRP) have been detected in several human tumour types. To study the current prevalence and recent epidemiological changes of Helicobacter pylori (H. A search algorithm was then used to cross-correlate the unknown with each IR spectrum in the subset of library spectra identified by the search prefilters. It will also be developed further, in order to target and reduce the new errors which have been reported. Pacemaker therapy, which has proved to be the only treatment for symptomatic bradyarrhythmias, exhibits great variation from country to country around the world. No effect of TETRA hand portable transmission signals on human cognitive function and symptoms. However, the prognostic significance of PTGER2 expression or its relationship with MSI, CIMP, LINE-1 hypomethylation, or PTGS2 (COX-2) remains uncertain. In order to know the causes by those which the patients have attended to be complained of the attention provided by a Obstetrician/Gynecologist (OG). Recent studies have focused on associations of the APOL1 risk variants with outcomes beyond kidney disease, including cardiovascular disease and mortality.

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The effect of low-dose haloperidol was different after naloxone treatment (0.2 mg/kg intranasally): the number of pup transfers increased significantly. In the present study, in samples of paediatric patients with benign IM and paediatric patients with malignant lymphomas, we detected previously described sequence variations as well as distinctive sequence polymorphisms from our region. Hybrid lighting-CPV, a new efficient concept mixing illumination with CPV. Improved restraint methods or alternative models in conscious animals should therefore be explored. Collection of reliable microbiologic data is critical in making a diagnosis as well as for treatment of infection, especially when osteomyelitis is concerned. Current methods to measure eye-hand coordination (EHC) have been widely applied in research and practical fields. However, little research examines the links between racial/ethnic HIV disparities via the Drug War, sexual risk, and stigma. Even if people are experts at understanding how various input cues landed them at a particular decision (something the authors refer to as cue utilization), they may still fail to appreciate how context influences the weight given to those input variables. The presentation of adrenal insufficiency varies dramatically and poses a major diagnostic dilemma. In both models, we found significant correlation between photon emission and infectious virus production.

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Lipid-based liquid crystalline nanoparticles (LCNPs) are interesting candidates for drug delivery applications, for instance as solubilizing or encapsulating carriers for intravenous (i.v.) drugs. To determine E-cadherin, beta-catenin and p120(ctn) expression phenotype in cuboidal and polygonal cells, which are the two major cell types in pulmonary sclerosing hemangiomas. In addition, enzyme activity was inhibited in the presence of the specific ecto-NTPDase inhibitor, ARL67156. To explore the relationship between protein kinase C (PKC) and invasion/metastasis of salivary adenoid cystic carcinoma and to explore the possibility of treatment against invasion/metastasis of the tumor cell by PKC inhibitor. They were exposed to soluble neurotrophins, cells transfected to secrete neurotrophins, and/or collagen gels. Bafilomycin A1 targets both autophagy and apoptosis pathways in pediatric B-cell acute lymphoblastic leukemia.

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Flowering is regulated by a network integrated from four major pathways, including the photoperiod, vernalization, gibberellin, and autonomous pathways. The effect of applying electric pulses to muscle tissue will be described in details, while present and future clinical applications are reviewed. The recovery rate of alcoholics 2 years after discharge from residential treatment was examined. Treatment of chronic hepatitis C with pegylated interferon-a and ribavirin is now adapted individually based on the virological response on treatment. Data included the OATD severity score, date of occurrence compared with the thyroid disease and determination of thyroid function and immune abnormalities. Immunosuppressive therapy dramatically reduced the expression of LAT making it an attractive therapeutic target in SAA. There is well documented evidence for the increase in widespread use of complementary and alternative medicine in the treatment of physical and psychiatric symptoms and disorders within the populations. This review summarizes the role of the Rap1 signal in developments and functions of the immune and hematopoietic systems as well as in malignancy. The KRAB/KAP1-miRNA regulatory cascade is evolutionarily conserved, as it also controls mitophagy during human erythropoiesis. We present a practical synthesis of Tamiflu by using novel synthetic routes, cheap reagents, and the abundantly available starting material D-glucal.

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