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Adapalene is used to treat acne. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Adapalene belongs to a class of medications called retinoids. It works by affecting the growth of cells and decreasing swelling and inflammation.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adina, Aditop, Adlene, Alangel, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

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Adapalene is used to treat acne. It works partly by keeping skin pores clear.

Adapalene is available only with your doctor's prescription.


Usual Adult Dose for Acne:

Adapalene 0.1% cream, 0.1% gel, 0.3% gel: Apply to the affected area once a day at bedtime after washing. A thin film should be applied, avoiding eyes, lips, angles of the nose, and mucous membranes. Lotion: Apply a thin film of lotion to the entire face and other affected areas of the skin once daily, after washing gently with a mild soapless cleanser. Dispense a nickel size amount of lotion (3 to 4 actuations of the pump) to cover the entire face. Avoid application to the areas of skin around eyes, lips and mucous membranes.

Usual Pediatric Dose for Acne:

Adapalene 0.1% cream, 0.1% gel, 0.3% gel: 11 years or less: Safety and efficacy have not been established. 12 to 18 years: Apply to the affected area once a day at bedtime after washing. A thin film should be applied, avoiding eyes, lips, angles of the nose, and mucous membranes. Safety and effectiveness of the lotion formulation in pediatric patients under the age of 12 have not been established.

Detailed Adapalene dosage information


If you overdose Adapalene and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Adapalene dosage information

Side effects

The most common side effects associated with Adapalene are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Adapalene if you are allergic to adapalene.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions.

It is not known whether adapalene passes into breast milk or if it could harm a nursing baby. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

It is not known whether Adapalene will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

Adapalene is not approved for use by anyone younger than 12 years old.

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Several different alleles of murM cloned in plasmid pLS578 and introduced into a murM deletion mutant of the penicillin-resistant strain Pen6 were able to reconstitute each one of the three mutant phenotypes: the highly branched cell wall structure, original high level of penicillin resistance, and normal sensitivity to lysis. Lactobacillus formosensis improved fermentability by reducing silage pH and improved aerobic stability by producing more propionate, which inhibited yeast activity. A single institution experience with the new bethesda system for reporting thyroid cytopathology: correlation with existing cytologic, clinical, and histological data. Proliferation, survival, and apoptosis signaling dysregulation can be identified in ovarian cancer effusion samples. Thus, the cup angles need to be planned with consideration of the effects of pelvic tilt. PWRI equivalent diameter expresses the PWRI through the diameter of the average AAA that has the same PWRI, i.e.

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Development of new therapeutic strategies to combat the economic impact of neosporosis remains an important scientific endeavor. Potential cost-effectiveness of a new infant tuberculosis vaccine in South Africa--implications for clinical trials: a decision analysis. C-terminal binding: an expanded repertoire and function of 14-3-3 proteins. In conjunction with SCD, CACSCs may be considered to improve articular cartilage damage. It has highly commercial and economic importance due to the presence of bioactive monoterpene indole alkaloids (MIAs) such as ajmaline, yohimbine, ajmalicine, serpentine and reserpine. Household surveys, before (2008) and after (2010) intervention, were conducted amongst all women who had given birth within the previous 12 months. Left ventricular diastolic dysfunction in chronic aortic dissection. TLR2 and TLR4 expression in atopic dermatitis, contact dermatitis and psoriasis.

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To investigate the effects of sodium hyaluronate in supplementary treatment of comminuted fracture of ankle. The incidence of dengue in Guangdong province had fallen steadily from 1978 to 2010. L-aspa should be stopped and further administration definitively avoided. Management of abdominal aortic aneurysms (AAAs) is based on diameter. Knowledge and attitude of dental professionals of north India toward plagiarism. Several important photolytic behaviors of NDMA photolysis regarding the roles of dissolved oxygen and solution pH were newly observed, and novel photolytic mechanisms were proposed based on these observations. Thecal cells were obtained from 23 women with PCOS and 51 controls. Insights into the binding of GABA to the insect RDL receptor from atomistic simulations: a comparison of models.

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avium DnaA protein, the counterpart of Escherichia coli replication initiator protein, was overproduced in E. In all, 34 retrospective studies evaluating 21 different markers complied with the inclusion criteria. However, in black patients, HD occurs predominantly on haplogroup B, suggesting several distinct origins of the mutation in South Africa. Retroviral transfer and expression of human MDR-1 in a murine haemopoietic stem cell line does not alter factor dependence, growth or differentiation characteristics. The twin arginine transport (Tat) system translocates folded proteins across the bacterial inner membrane. This study evaluated the relationships between the WPAI-AS and other outcome measures in AR. Although there is evidence of some benefits of 5-fluorouracil (5-FU), the most commonly used drug in colon cancer therapy, it still remains unsatisfactory because of intrinsic or acquired drug resistance. Furthermore, we demonstrated that item wording may have an impact on commenting (Study 3) and should be considered as a potential lever for training professionals to influence commenting behavior from trainees.

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Acute respiratory infections (ARIs) are the leading cause of death among children less than 5 years in India. This preliminary study investigated the efficacy of training to improve inhibitory control (IC), a process linked to overeating, on consumption and cognitive control factors. Mechanistic investigations using ESI-MS revealed that the transesterification catalyzed by these complexes proceeds through two types of acyl intermediates. Adaptability is measured as the average variation of the hydrophobicity that the lipitor 80 mg daily encoded amino acids undergo when errors or mutations are present in the codons of the hypothetical codes. PH-20, which is a glycosylphosphatidylinositol-anchored hyaluronidase located on the head of sperm, has important functions in fertilization. Tubularized Incised Plate (TIP) urethroplasty is a technique for urethral reconstruction of hypospadias although there are some controversies for its use in recurrent cases. Little has been published on the progression of non-cystic fibrosis bronchiectasis (BX), especially in childhood. To achieve this, B cells differentiate into specialized subpopulations, which perform unique functions in response to antigen. However, both the etiology and mechanisms associated with SHS are still unclear. Medical school electives and recruitment into psychiatry : a 20-year experience.

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Here we show that these shortcomings can be overcome by using the acyl carrier protein labeling technique. Smoking Habits and Attitudes in Students of the Third Faculty of Medicine of Charles University in Prague. Antiviral therapy should be considered in HBV-infected patients with HCC, especially to prevent tumor recurrence after curative-intended therapy or to prevent hepatic decompensation. Seven distinct fluids representative of putative martian groundwater were used to calculate Gibbs energy values in the presence of dissolved methane under a range of atmospheric CO2 partial pressures. The alveolar subtype harbors a translocation-mediated PAX3:FOXO1A fusion gene and has an extremely poor prognosis.

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The sequential therapy regimen for Helicobacter pylori eradication. The OXR domain defines a conserved family of eukaryotic oxidation resistance proteins. There are currently no standards for the initiation of prophylactic anticoagulation in trauma patients with blunt liver and spleen injuries. Electrophoretic mobility shift assays indicated that PDTC prevents NF-kappaB induction. Transplanted neural precursor cells reduce brain inflammation to attenuate chronic experimental autoimmune encephalomyelitis. Coronary artery bypass grafting with left internal mammary artery and right gastroepiploic artery, with and without bypass. Existing natural media painting simulations have produced high-quality results, but have required powerful compute hardware and have been limited to screen resolutions. Protein expression of ERK 1/2 and Akt was examined using western blotting. Listeria monocytogenes can form biofilms in tap water and enter into the viable but non-cultivable state. Commentary: an anatomical alternative to improve circulation to the spinal cord after stent-graft placement.

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Lung cancer radiation therapy (RT) is associated with complex geometrical uncertainties, such as respiratory motion, differential baseline shifts between primary tumor and involved lymph nodes, and anatomical changes due to treatment response. The development of new antidepressants targeting novel pathways opens a promising perspective for the management of TRD. Yet, precise and reliable methods for specific expression of optogenetic tools remain challenging. Most notably, instructions were conveyed with the UMS, which uses standard intervals for expressing when to take medicine (morning, noon, evening, bedtime). We found an increase of blood NK cells in three patients with a severe phenotype. Effect of Educational Intervention on Perceived Susceptibility Self-Efficacy and DMFT of Pregnant Women.

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Characterization of nonspherical atmospheric aerosol particles with electrooptical nephelometry. The purpose of this study is to prepare, characterize and evaluate the in vitro efficacy of curcumin loaded poly-hydroxyethyl methacrylate/stearic acid nanoparticles in MCF-7. Engineered BGMK cells for sensitive and rapid detection of enteroviruses. Memorial metal ball for the treatment of avascular necrosis of femoral head. Higher levels of physical activity are linked to larger cerebral volumes, lower rates of atrophy, better cognitive function and a lower risk of cognitive decline and dementia. A TDDFT study on the excited-state intramolecular proton transfer (ESIPT): excited-state equilibrium induced by electron density swing. Recurrence is the major factor influencing the clinical outcome of meningioma patients although the exact relationship between primary and recurrent tumors still needs to be clarified. Achromatic interferometers are developed that perform optical processing operations and record both the phase and amplitude of the output by means of a coherent reference beam.

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Advanced contrast modalities for X-ray radiology: Phase-contrast and dark-field imaging using a grating interferometer. Skills mix: future health policy and workforce planning in primary care. Osteogenetic property of a biodegradable three-dimensional macroporous hydrogel coating on titanium implants fabricated via EPD. Recent guidelines from the American Heart Association and the American College of Cardiology encourage a more aggressive approach to lipid lowering in women. mRNA levels of mTOR, PTEN, IGF-1R, and 4EBP1 were evaluated by RT-PCR and protein expression of mTOR, PTEN, and IGF-1R by immunohistochemistry (IHC).

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